Pentobarbital will decrease the extent or impact of voriconazole by influencing hepatic enzyme CYP2C9/10 metabolism. Slight/Significance Mysterious. pentobarbital will decrease the level or result of isavuconazonium sulfate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. pentobarbital will minimize the extent or influence of capivasertib by affecting hepat... https://shanejnwjs.blogoscience.com/37108709/is-nembutal-a-barbiturate-fundamentals-explained