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Background: Astrocytes regulate neuronal function. synaptic formation and maintenance partly through secreted extracellular vesicles (EVs). In amyotrophic lateral sclerosis (ALS) astrocytes display a toxic phenotype that contributes to motor neuron (MN) degeneration. Methods: We used human induced astrocytes (iAstrocytes) from 3 ALS patients carrying C9orf72 mutations and 3 non-affect... https://www.chiggate.com/eeboo-memory-matching-game-animal-pre-school-supply/

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