Butabarbital and olopatadine intranasal each improve sedation. Avoid or Use Alternate Drug. Coadministration increases danger of CNS despair, which can cause additive impairment of psychomotor functionality and induce daytime impairment. butabarbital will decrease the extent or result of sufentanil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unknown. b... https://alexisg075wtv8.sunderwiki.com/user