"Benadryl addiction" most often refers to the psychological dependence one feels. The primary signs and characteristics of any psychological dependence would be the need to take the drug to either sleep or relax, increasing doses over a certain period of time, and becoming irritated or cranky unless the drug is being used. Some side effects can come about due to overuse, which may inc... https://secondnewlife.com/how-long-benadryl-stays-in-your-system/